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High Asymptomatic Carriage With the Omicron Variant in South Africa.
Garrett, Nigel; Tapley, Asa; Andriesen, Jessica; Seocharan, Ishen; Fisher, Leigh H; Bunts, Lisa; Espy, Nicole; Wallis, Carole L; Randhawa, April Kaur; Miner, Maurine D; Ketter, Nzeera; Yacovone, Margaret; Goga, Ameena; Huang, Yunda; Hural, John; Kotze, Philip; Bekker, Linda Gail; Gray, Glenda E; Corey, Lawrence.
Clin Infect Dis ; 75(1): e289-e292, 2022 08 24.
Article in English | MEDLINE | ID: covidwho-1769236

ABSTRACT

We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4 + T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive.


Subject(s)
COVID-19 , SARS-CoV-2 , Humans , Polymerase Chain Reaction , South Africa/epidemiology
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